Not a curative treatment for angina attacks, nor as initial treatment for unstable angina or MI, nor in pre-hospital phase or during 1st days of hospitalisation. Worsen parkinsonian symptoms (tremor, akinesia, hypertonia). Falls related to gait instability or hypotension. Fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. May affect ability to drive & use machines. Moderate renal impairment. Avoid use during pregnancy. Not to be used during lactation. Childn <18 yr. Elderly >75 yr.